Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127088 | 0.95 | HTT (0.47) | HTTKDM4EGAAL3MBTL1HSD17B10 | |
| SCHEMBL1127247 | 0.91 | HTT (0.48) | HTTKDM4EGAAL3MBTL1HSD17B10 | |
| SCHEMBL1126705 | 0.81 | HTT (0.50) | HTTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1126842 | 0.79 | HTT (0.42) | HTTKDM4EHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL1127356 | 0.78 | HTT (0.41) | HTTGAAHSD17B10ALDH1A1HPGD | |
| SCHEMBL11172051 | 0.77 | MAPT (0.49) | HTTSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL1126606 | 0.74 | CDC7 (0.46) | HTTKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1127151 | 0.74 | HTT (0.43) | HTTHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL1126627 | 0.72 | HTT (0.45) | HTTKDM4EHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL1127274 | 0.72 | HTT (0.44) | HTTKDM4EL3MBTL1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |