Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.53 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.53 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277040 | 0.92 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11280417 | 0.89 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11277927 | 0.84 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11271593 | 0.82 | ALDH1A1 (0.47) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL409741 | 0.81 | HMOX1 (0.72) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11273140 | 0.80 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7527357 | 0.79 | HMOX1 (0.70) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| Bromide SCHEMBL29223796 | 0.79 | HMOX1 (0.70) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11276474 | 0.78 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11643282 | 0.78 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |