Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783162 | 0.73 | TSHR (0.36) | PKMALDH1A1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9666353 | 0.72 | CYP4F2 (0.56) | ALDH1A1L3MBTL1KDM4EMAPK1NLRP3 | |
| SCHEMBL102804 | 0.72 | PNMT (0.46) | ALDH1A1PNMTIDO1 | |
| SCHEMBL30962862 | 0.72 | PNMT (0.46) | ALDH1A1PNMTIDO1 | |
| SCHEMBL23616906 | 0.71 | AKR1B1 (0.47) | ALDH1A1IDO1CYP2D6MAPT | |
| SCHEMBL15771305 | 0.71 | IDO1 (0.43) | ALDH1A1L3MBTL1KDM4EMAPK1PNMT | |
| SCHEMBL11267255 | 0.71 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EMAPK1HPGDLMNA | |
| SCHEMBL28899623 | 0.70 | IDO1 (0.40) | PKMALDH1A1IDO1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL11833876 | 0.70 | PNMT (0.45) | ALDH1A1PNMTIDO1 | |
| SCHEMBL16397052 | 0.69 | AKR1B1 (0.57) | HPGDLMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337357-A | 1,4-BENZOTHIAZINE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4268301-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-19 | — | — | US | disclosed |