Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626544 | 0.84 | PNMT (0.48) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL28842276 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAGFERHPGD | |
| SCHEMBL16410217 | 0.83 | MTNR1A (0.43) | TTRUSP2LMNACYP2C9TBXA2R | |
| SCHEMBL29498164 | 0.82 | NPC1 (0.52) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL872658 | 0.82 | NPC1 (0.52) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL16112452 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL17398610 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL30296851 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ETTRUSP2LMNA | |
| SCHEMBL16397052 | 0.79 | AKR1B1 (0.57) | TTRLMNACYP2C9HPGDAKR1B10 | |
| SCHEMBL31619490 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ETTRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55130954-A | — | — | None | — | — | JP | disclosed |
| US-4337357-A | 1,4-BENZOTHIAZINE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4268301-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-19 | — | — | US | disclosed |
| JP-S55130954-A | PHENYLTHIOACETIC ACID ESTER DERIVATIVE, ITS PREPARATION, AND HERBICIDE CONTAINING SAID COMPOUND AS EFFECTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1980-10-11 | — | — | JP | disclosed |