Netivudine

Netivudine

SCHEMBL112726

CC#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.63
TK2 O00142 2/20 0.58
SLC28A1 O00337 1/20 0.54
SLC28A2 O43868 1/20 0.54
SLC29A1 Q99808 1/20 0.54
SLC28A3 Q9HAS3 1/20 0.54
DNPH1 O43598 1/20 0.47
P2RY2 P41231 3/20 0.47
TSHR P16473 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
PMP22 Q01453 1/20 0.45
HBB P68871 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TYMP P19971 1/20 0.45
P2RY6 Q15077 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Netivudine SCHEMBL913358 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL18052692 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL6153401 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL112727 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL9538356 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL1585773 1.00 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL462884 0.97 PYGM (0.60) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL22028728 0.92 P2RY6 (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL21276349 0.91 PYGM (0.51) PYGMTK2DNPH1P2RY2TSHR
SCHEMBL1060638 0.90 PYGM (0.51) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10522 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
EP-4740010-A1 NEGATIVE TUNE STANDARD FOR MASS SPECTROMETRY Agilent Technologies, Inc. (US) 2026-05-13 EP claimed
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 US claimed
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 US claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-20260028616-A1 METHODS AND APPARATUS FOR DUPLEX NUCLEOTIDE PURIFICATION AGILENT TECHNOLOGIES, INC. (US) 2026-01-29 US claimed
EP-4677078-A1 MANUFACTURE OF MESSENGER RNA WITH KP34 POLYMERASE Sanofi Pasteur Inc. (US) 2026-01-14 EP claimed
JP-2002523335-A 2002-07-30 JP claimed
EP-1102842-A2 ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION Aventis Pharma Deutschland GmbH (DE) 2001-05-30 EP claimed
US-6056859-A Method and apparatus for staining immobilized nucleic acids LOCKHEED MARTIN ENERGY RESEARCH CORPORATION (US) 2000-05-02 US claimed
WO-2000008140-A2 ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-02-17 WO claimed
EP-0978561-A1 Antisense oligonucleotides for the inhibition of VEGF expression Hoechst Marion Roussel Deutschland GmbH (DE) 2000-02-09 EP claimed
JP-2682739-B2 1997-11-26 JP claimed
EP-0550580-A1 URACIL REDUCTASE INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1993-07-14 EP claimed
EP-0539442-A1 ENZYME INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1993-05-05 EP claimed
WO-1992004901-A1 URACIL REDUCTASE INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1992-04-02 WO claimed
WO-1992001452-A1 ENZYME INACTIVATORS THE WELLCOME FOUNDATION LIMITED (GB) 1992-02-06 WO claimed