Netivudine

Netivudine

SCHEMBL462884

C#CC.CC#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.60
TK2 O00142 2/20 0.55
SLC28A1 O00337 1/20 0.51
SLC28A2 O43868 1/20 0.51
SLC29A1 Q99808 1/20 0.51
SLC28A3 Q9HAS3 1/20 0.51
DNPH1 O43598 1/20 0.45
P2RY2 P41231 3/20 0.45
TYMP P19971 1/20 0.43
ADK P55263 1/20 0.43
DOT1L Q8TEK3 1/20 0.43
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
PMP22 Q01453 1/20 0.43
HBB P68871 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Netivudine SCHEMBL112726 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL18052692 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL112727 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL913358 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL9538356 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL1585773 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL6153401 0.97 PYGM (0.63) PYGMTK2SLC28A1SLC28A2SLC29A1
Netivudine SCHEMBL22028728 0.89 P2RY6 (0.57) PYGMTK2SLC28A1SLC28A2SLC29A1
SCHEMBL21276349 0.87 PYGM (0.51) PYGMTK2DNPH1P2RY2TSHR
SCHEMBL22143603 0.87 PYGM (0.66) PYGMTK2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120021427-A1 Methods For Rapid Forensic DNA Analysis IBIS BIOSCIENCE, INC (US) 2012-01-26 US disclosed