Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270036 | 1.00 | NPC1 (0.43) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11274274 | 1.00 | NPC1 (0.43) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11267616 | 0.94 | TP53 (0.45) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11261813 | 0.88 | TP53 (0.47) | TP53TSHRALDH1A1PTGS2MAPK1 | |
| SCHEMBL11293537 | 0.86 | NPC1 (0.47) | NPC1JAK2RAB9APAX8TP53 | |
| SCHEMBL11259796 | 0.81 | TP53 (0.46) | TP53TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11256206 | 0.80 | PTGS2 (0.43) | NPC1JAK2RAB9APAX8PTGS2 | |
| SCHEMBL11244137 | 0.80 | PTGS2 (0.43) | NPC1JAK2RAB9APAX8PTGS2 | |
| SCHEMBL11246798 | 0.80 | PTGS2 (0.43) | NPC1JAK2RAB9APAX8PTGS2 | |
| SCHEMBL11247829 | 0.78 | PTGS2 (0.42) | NPC1JAK2RAB9APAX8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313892-A | VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4248805-A | Vulcanizable rubber compositions containing N-(sulfenyl) phthalamides as scorch inhibitors | MONSANTO COMPANY (US) | 1981-02-03 | — | — | US | disclosed |