SCHEMBL11261813

SCHEMBL11261813

CCCSN(C(=O)c1ccccc1C(=O)N(SCCC)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.47
POLB P06746 3/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
GLA P06280 1/20 0.41
PTGS2 P35354 1/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11267616 0.90 TP53 (0.45) TP53POLBALDH1A1TSHRGLA
SCHEMBL11274274 0.88 NPC1 (0.43) TP53ALDH1A1TSHRPTGS2MAPK1
SCHEMBL11270036 0.88 NPC1 (0.43) TP53ALDH1A1TSHRPTGS2MAPK1
SCHEMBL11272871 0.88 NPC1 (0.43) TP53ALDH1A1TSHRPTGS2MAPK1
SCHEMBL11259796 0.86 TP53 (0.46) TP53POLBALDH1A1TSHRGLA
SCHEMBL11244321 0.78 ALDH1A1 (0.39) TP53ALDH1A1TSHRGLAPTGS2
SCHEMBL11264516 0.77 POLB (0.49) TP53POLBALDH1A1TSHRGLA
SCHEMBL11270200 0.75 TP53 (0.42) TP53POLBALDH1A1TSHRGLA
SCHEMBL11269472 0.74 TP53 (0.41) TP53POLBALDH1A1TSHRGLA
SCHEMBL11272720 0.72 POLB (0.45) TP53POLBALDH1A1TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313892-A VULCANIZATION INHIBITORS MONSANTO COMPANY (US) 1982-02-02 US disclosed
US-4248805-A Vulcanizable rubber compositions containing N-(sulfenyl) phthalamides as scorch inhibitors MONSANTO COMPANY (US) 1981-02-03 US disclosed