Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278172 | 0.82 | CNR2 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL23779608 | 0.82 | CNR2 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL23779674 | 0.82 | HSD17B10 (0.40) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL11275892 | 0.79 | MAPT (0.38) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL11483862 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL23779519 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL23779571 | 0.74 | JAK2 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL6646384 | 0.74 | SCN10A (0.51) | ALDH1A1KDM4EMEN1KMT2ASCN10A | |
| SCHEMBL23779540 | 0.74 | SCN10A (0.51) | ALDH1A1KDM4EMEN1KMT2ASCN10A | |
| SCHEMBL30468364 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |