Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277095 | 0.84 | SCN10A (0.41) | LMNAPOLBNPY5RTSHRGAA | |
| SCHEMBL11273173 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1POLBGAA | |
| SCHEMBL10924538 | 0.75 | LMNA (0.47) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11280244 | 0.71 | OPRK1 (0.43) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL30468364 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL20472500 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL31374761 | 0.70 | HSD17B10 (0.40) | ALDH1A1KMT2AMEN1TSHRRXFP1 | |
| SCHEMBL2437655 | 0.68 | AKR1C4 (0.41) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL30483667 | 0.68 | AKR1C4 (0.41) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL10926941 | 0.68 | KMT2A (0.70) | MAPTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |