SCHEMBL11273183

SCHEMBL11273183

CCN(CC)CCC(C)Nc1cccc(C(c2ccccc2Cl)c2cccc(NC(C)CCN(CC)CC)c2Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 1/20 0.38
MC4R P32245 1/20 0.38
CACNA2D1 P54289 5/20 0.37
TMEM97 Q5BJF2 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PRNP P04156 1/20 0.37
APP P05067 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37
NQO2 P16083 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
CHRM3 P20309 1/20 0.37
MTOR P42345 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5007883 0.81 CCR4 (0.49) CCR4CACNA2D1TMEM97SIGMAR1CYP2D6
SCHEMBL11273187 0.74 MAPT (0.40) MC4RSIGMAR1CYP2D6MAPTMEN1
SCHEMBL3903278 0.68 MAPT (0.36) CCR4MC4RTDP1MAPTMEN1
SCHEMBL3903276 0.64 MAPT (0.63) MC4RSIGMAR1CYP2D6CYP2C19TDP1
Nitrogen SCHEMBL10786231 0.63 KCNQ2 (0.46) TDP1MAPTMEN1KMT2AHTT
SCHEMBL2066643 0.62 TSHR (0.53) CYP2D6CYP2C19TDP1ADRA2AMAPT
SCHEMBL8165529 0.62 MEN1 (0.43) CYP2D6MAPTMEN1KMT2A
SCHEMBL11277416 0.60 SMN1; SMN2 (0.47) SIGMAR1CYP2D6TDP1
SCHEMBL21789895 0.60 TAS1R3 (0.38) CYP2C19MAPTPKMHTT
SCHEMBL29385988 0.59 TSHR (0.58) SIGMAR1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed