SCHEMBL2066643

SCHEMBL2066643

Clc1ccccc1C(c1ccccc1Cl)c1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 2/20 0.46
IDO1 P14902 2/20 0.46
TDO2 P48775 2/20 0.46
IDO2 Q6ZQW0 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 1/20 0.46
KDM4E B2RXH2 1/20 0.46
NR1I2 O75469 1/20 0.46
ABCB11 O95342 1/20 0.46
NR3C1 P04150 1/20 0.46
PGR P06401 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL41575 0.84 IDO1 (0.55) TSHRLMNAMAPTMEN1KMT2A
2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL29279416 0.82 IDO1 (0.57) TSHRLMNAMAPTMEN1KMT2A
Dimethylamine SCHEMBL10777188 0.80 MAPT (0.48) TSHRLMNAMAPTMEN1KMT2A
SCHEMBL11617245 0.79 TSHR (0.50) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL30848757 0.79 TSHR (0.50) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL947512 0.79 TSHR (0.50) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL11606505 0.79 TSHR (0.50) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL24017077 0.77 IDO1 (0.48) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL84509 0.77 GABRA1 (0.50) TSHRLMNAMAPTHIF1AIDO1
SCHEMBL12204154 0.77 ADRB2 (0.48) TSHRLMNAMAPTHIF1AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP claimed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US claimed
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
EP-3130612-B1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN-BASED POLYMER IDEMITSU KOSAN CO (JP) 2023-09-06 EP disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-3130613-B1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST IDEMITSU KOSAN CO (JP) 2021-03-10 EP disclosed
US-10246531-B2 Production method for olefin-based polymer, olefin polymerization catalyst, and olefin-based polymer IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed
US-10150825-B2 Production method for olefin-based polymer, and olefin polymerization catalyst IDEMITSU KOSAN CO., LTD. (JP) 2018-12-11 US disclosed
EP-3130613-A1 PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST Idemitsu Kosan Co., Ltd (JP) 2017-02-15 EP disclosed
EP-1498432-A1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-01-19 EP disclosed
EP-1477499-A1 HIGHLY FLOWABLE 1-BUTENE POLYMER AND PROCESS FOR PRODUCING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-11-17 EP disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0707014-B1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN CO (JP) 1999-02-17 EP disclosed
US-5747613-A Process for producing aromatic vinyl compound-based copolymer IDEMITSU KOSAN CO., LTD. (JP) 1998-05-05 US disclosed
EP-0707014-A1 PROCESS FOR PRODUCING AROMATIC VINYL COMPOUND COPOLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 TSHR 606/4885LMNA 1550/4885MAPT 4097/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 TSHR 606/4885LMNA 1550/4885MAPT 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.