Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273290 | 0.95 | MEN1 (0.37) | MEN1ALDH1A1GAAKMT2AKDM1A | |
| SCHEMBL11260229 | 0.78 | HTR2A (0.39) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11270222 | 0.76 | HTR2A (0.38) | ALDH1A1GAAHTR2AHTR2CHTR2B | |
| SCHEMBL11275332 | 0.75 | MAPT (0.36) | MEN1ALDH1A1GAAKMT2AHTR2C | |
| SCHEMBL11272332 | 0.74 | BCHE (0.35) | MEN1ALDH1A1GAAKMT2AKDM1A | |
| Hydrochloric Acid SCHEMBL11273176 | 0.74 | MAPT (0.35) | ALDH1A1GAAHTR2C | |
| SCHEMBL11263563 | 0.74 | HTR2C (0.39) | ALDH1A1HTR2AHTR2C | |
| SCHEMBL11262097 | 0.74 | HTR2C (0.39) | MEN1ALDH1A1GAAKMT2AHTR2A | |
| SCHEMBL11276985 | 0.74 | CA1 (0.34) | — | |
| SCHEMBL25786676 | 0.74 | BCHE (0.39) | BCHEHTR5AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |