Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483025 | 0.80 | SLC6A2 (0.33) | — | |
| SCHEMBL10563497 | 0.71 | KDM4E (0.34) | SMN1; SMN2 | |
| SCHEMBL18526279 | 0.69 | TSHR (0.33) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL16810704 | 0.68 | — | — | |
| SCHEMBL896075 | 0.67 | CHRM3 (0.39) | TSHRSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL11903300 | 0.67 | GLA (0.31) | — | |
| SCHEMBL17590183 | 0.66 | — | — | |
| SCHEMBL31097019 | 0.66 | CHRM3 (0.35) | TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11179673 | 0.66 | MAOA (0.37) | TSHRSMN1; SMN2TDP1 | |
| SCHEMBL16599541 | 0.65 | CA1 (0.36) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046377-A1 | Cycloalkenylcarboxamido derivatives of tetramisole, their preparation and use in medicine | BEECHAM GROUP PLC (GB) | 1982-02-24 | — | — | EP | disclosed |