SCHEMBL11903300

SCHEMBL11903300

CC(=O)OC1=CC(C)(C)CC=C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16380913 0.84
SCHEMBL11610762 0.70 CYP3A4 (0.39) LMNA
SCHEMBL11789705 0.69 NR3C1 (0.35) LMNA
SCHEMBL11902996 0.67 GLA (0.33) GLALMNA
SCHEMBL11273637 0.67 TSHR (0.31)
SCHEMBL16167274 0.65 GLA (0.33) GLALMNA
SCHEMBL8530508 0.64 GLA (0.35) GLALMNA
SCHEMBL30291076 0.64 GLA (0.32) GLALMNA
SCHEMBL7316737 0.62
SCHEMBL11707354 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927750-B2 Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules UNIVERSITAET ZU KOELN (DE) 2015-01-06 US disclosed
US-8927750-B2 Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules UNIVERSITAET ZU KOELN (DE) 2015-01-06 US disclosed
US-8927750-B2 Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules UNIVERSITAET ZU KOELN (DE) 2015-01-06 US disclosed
US-20120202774-A1 ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES UNIVERSITAET REGENSBURG (DE) 2012-08-09 US disclosed
US-20120202774-A1 ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES UNIVERSITAET REGENSBURG (DE) 2012-08-09 US disclosed
US-20120202774-A1 ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES UNIVERSITAET REGENSBURG (DE) 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202774-A1 ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES PPOX, APEH, ACOX3 GLA 1714/4885LMNA 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.