SCHEMBL11273693

SCHEMBL11273693

O=C(O)c1ccc(OCc2ccccc2)cc1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 6/20 0.96
NR4A1 P22736 1/20 0.96
NR4A3 Q92570 1/20 0.96
SRD5A2 P31213 2/20 0.87
PLA2G4B P0C869 1/20 0.81
MAOB P27338 1/20 0.72
PARP10 Q53GL7 1/20 0.72
RXRA P19793 5/20 0.70
RXRB P28702 5/20 0.70
NPC1 O15118 1/20 0.70
POLB P06746 1/20 0.70
RAB9A P51151 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
RXRG P48443 1/20 0.67
PKM P14618 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830467 0.98 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL228477 0.98 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL4059143 0.98 NR4A2 (1.00) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11603952 0.96 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL11603274 0.96 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Hydrochloric Acid SCHEMBL8544438 0.96 NR4A2 (0.96) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL4949143 0.93 NR4A2 (0.90) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
SCHEMBL1221359 0.93 NR4A2 (0.90) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Benzil SCHEMBL7771752 0.91 NR4A2 (0.87) NR4A2NR4A1NR4A3SRD5A2PLA2G4B
Hydrochloric Acid SCHEMBL8378883 0.91 NR4A2 (0.87) NR4A2NR4A1NR4A3SRD5A2PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US claimed
US-4352792-A 3-Alkoxyflavone antiviral agents HOFFMANN-LA ROCHE INC. (US) 1982-10-05 US disclosed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US disclosed