Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CDC25B | P30305 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671336 | 0.93 | TSHR (0.73) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL2569253 | 0.93 | TSHR (0.73) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL28416763 | 0.86 | TSHR (0.63) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL9150759 | 0.85 | TSHR (0.73) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL23484418 | 0.84 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL27560307 | 0.83 | TSHR (0.59) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL5946756 | 0.83 | ALDH1A1 (0.65) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL11749538 | 0.83 | TSHR (0.59) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL4877934 | 0.83 | TSHR (0.59) | TSHRHSD17B10ALDH1A1CDC25BKDM4E | |
| SCHEMBL870574 | 0.81 | BRD4 (0.51) | TSHRHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567442-B | Inhibitors of hepatitis C virus polymerase | 共晶制药公司 | 2021-05-25 | — | — | CN | disclosed |
| US-10947210-B2 | Inhibitors of Hepatitis C virus polymerase | COCRYSTAL PHARMA, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-10947210-B2 | Inhibitors of Hepatitis C virus polymerase | COCRYSTAL PHARMA, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200255393-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA, INC. | 2020-08-13 | — | — | US | disclosed |
| US-20200255393-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA, INC. | 2020-08-13 | — | — | US | disclosed |
| US-10464914-B2 | Inhibitors of hepatitis C virus polymerase | COCRYSTAL PHARMA, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-10464914-B2 | Inhibitors of hepatitis C virus polymerase | COCRYSTAL PHARMA, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| EP-3274340-B1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA INC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20180050998-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA, INC. | 2018-02-22 | — | — | US | disclosed |
| US-20180050998-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA, INC. | 2018-02-22 | — | — | US | disclosed |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9656981-B2 | Peripherally-acting cannabinoid receptor agonists for chronic pain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-23 | — | — | US | disclosed |
| WO-2016154241-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL PHARMA, INC. (US) | 2016-09-29 | — | — | WO | disclosed |
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-27 | — | — | US | disclosed |
| WO-2014015298-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-23 | — | — | WO | disclosed |
| US-4315088-A | COORDINATION CATALYST | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | TSHR 1275/4885HSD17B10 3930/4885ALDH1A1 3666/4885 |
| US-20200255393-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | POLI, POLR2E, POLR2H | TSHR 4606/4885HSD17B10 919/4885ALDH1A1 114/4885 |
| US-10464914-B2 | Inhibitors of hepatitis C virus polymerase | POLI, POLR2E, POLR2H | TSHR 4606/4885HSD17B10 919/4885ALDH1A1 114/4885 |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | TSHR 1275/4885HSD17B10 3930/4885ALDH1A1 3666/4885 |
| US-10947210-B2 | Inhibitors of Hepatitis C virus polymerase | POLI, POLR2E, POLR2H | TSHR 4606/4885HSD17B10 919/4885ALDH1A1 114/4885 |
| US-20180050998-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | POLI, POLR2E, POLR2H | TSHR 4606/4885HSD17B10 919/4885ALDH1A1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.