Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 4/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274111 | 0.98 | SIGMAR1 (0.50) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL11262734 | 0.96 | CYP1A2 (0.50) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL11255472 | 0.91 | KDM5A (0.41) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL6338008 | 0.89 | CYP1A2 (0.52) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL23158250 | 0.85 | CYP1A2 (0.35) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL27694515 | 0.82 | — | — | |
| SCHEMBL27390168 | 0.82 | SIGMAR1 (0.47) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL8124638 | 0.81 | SIGMAR1 (0.54) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL20902891 | 0.80 | CYP1A2 (0.44) | SIGMAR1CYP1A2MEN1CYP3A4KMT2A | |
| SCHEMBL8025386 | 0.79 | KDM5A (0.51) | SIGMAR1CYP1A2KDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046961-A1 | Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-10 | — | — | EP | disclosed |