Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274166 | 0.91 | SIGMAR1 (0.47) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL27694515 | 0.91 | — | — | |
| SCHEMBL11274111 | 0.90 | SIGMAR1 (0.50) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL11262734 | 0.87 | CYP1A2 (0.50) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL20343055 | 0.81 | LMNA (0.36) | SIGMAR1CYP1A2HTTMAPTLMNA | |
| SCHEMBL23158250 | 0.81 | CYP1A2 (0.35) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL6338008 | 0.80 | CYP1A2 (0.52) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL12513177 | 0.77 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL8023937 | 0.77 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL9978410 | 0.77 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046961-A1 | Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-10 | — | — | EP | disclosed |