Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | YARS1 | P54577 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817270 | 0.92 | TSHR (0.48) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11279778 | 0.91 | TSHR (0.47) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL10816879 | 0.89 | TSHR (0.43) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11269448 | 0.82 | YARS1 (0.46) | TSHRKDM4EGAATDP1KMT2A | |
| SCHEMBL11456692 | 0.80 | TOP1 (0.46) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11458211 | 0.80 | TSHR (0.44) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11474970 | 0.76 | KDM4E (0.54) | TSHRKDM4ETDP1KMT2A | |
| SCHEMBL11487916 | 0.74 | FOLH1 (0.48) | KDM4EALDH1A1TDP1KMT2AATM | |
| SCHEMBL10437840 | 0.74 | TOP1 (0.59) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL11271511 | 0.73 | CA1 (0.43) | TSHRRAB9AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341776-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4328224-A | ANTIBIOTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4301161-A | BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4298605-A | ANTIBIOTICS, BACTERICIDES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |