Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279778 | 0.89 | TSHR (0.47) | TOP1CA1CA2TSHRALDH1A1 | |
| SCHEMBL10817270 | 0.81 | TSHR (0.48) | TOP1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL11274306 | 0.80 | TSHR (0.45) | TOP1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL11686530 | 0.80 | CA1 (0.43) | CA1CA2TSHRALDH1A1KDM4E | |
| SCHEMBL11685412 | 0.79 | CA1 (0.39) | CA1CA2TSHRALDH1A1ATM | |
| SCHEMBL11458211 | 0.77 | TSHR (0.44) | TOP1CA1CA2TSHRALDH1A1 | |
| SCHEMBL10816879 | 0.76 | TSHR (0.43) | TOP1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL11685522 | 0.75 | LMNA (0.45) | CA1CA2ALDH1A1KDM4ERAB9A | |
| SCHEMBL11271511 | 0.75 | CA1 (0.43) | TOP1CA1CA2TSHRALDH1A1 | |
| SCHEMBL11685611 | 0.74 | FPR2 (0.44) | CA1CA2ALDH1A1ATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |