Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279778 | 0.88 | TSHR (0.47) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL11685012 | 0.81 | ALDH1A1 (0.42) | TSHRALDH1A1CA1CA2ATM | |
| SCHEMBL10437840 | 0.81 | TOP1 (0.59) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL10817270 | 0.80 | TSHR (0.48) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL11274306 | 0.80 | TSHR (0.45) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL11686316 | 0.78 | KDM4E (0.44) | GAAKDM4EALDH1A1CCR5HTT | |
| SCHEMBL11456692 | 0.77 | TOP1 (0.46) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL11685052 | 0.76 | NAALAD2 (0.43) | ALDH1A1CA1CA2ATM | |
| SCHEMBL10816879 | 0.76 | TSHR (0.43) | TSHRGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL11467309 | 0.74 | RAB9A (0.54) | TSHRGAAKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |