Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932230 | 0.90 | HSPB1 (0.82) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL11198841 | 0.86 | HSPB1 (0.75) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL6204892 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL4716681 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL29351868 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL6331907 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL9449124 | 0.84 | HSPB1 (1.00) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL177664 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL10468493 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL10466511 | 0.84 | HSPB1 (0.73) | HSPB1MAPTNPSR1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543167-B | Isothiazole compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-4334912-A | HERBICIDES WHICH ARE NONPHYTOTOXIC TO CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-15 | — | — | US | disclosed |