Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283747 | 0.87 | KDM4E (0.51) | HSD17B10TSHRKDM4EALDH1A1MAOB | |
| SCHEMBL11277143 | 0.85 | RECQL (0.53) | HSD17B10TSHRKDM4EALDH1A1MAOB | |
| SCHEMBL11416700 | 0.85 | MAOB (0.61) | HSD17B10TSHRKDM4EALDH1A1MAOB | |
| SCHEMBL11376692 | 0.85 | TSHR (0.55) | HSD17B10TSHRKDM4EALDH1A1PKM | |
| SCHEMBL11419618 | 0.84 | ALDH1A1 (0.51) | TSHRKDM4EALDH1A1MAOBPKM | |
| SCHEMBL11278189 | 0.82 | KDM4E (0.50) | HSD17B10TSHRKDM4EALDH1A1GAA | |
| SCHEMBL11269004 | 0.81 | EGFR (0.43) | HSD17B10TSHRKDM4EALDH1A1GAA | |
| SCHEMBL10411300 | 0.78 | ALDH1A1 (0.58) | HSD17B10TSHRKDM4EALDH1A1GAA | |
| SCHEMBL10654954 | 0.76 | KDM4E (0.47) | HSD17B10TSHRKDM4EALDH1A1PKM | |
| SCHEMBL8106509 | 0.75 | AKR1B1 (0.56) | TSHRMAOBAKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110464-A | INDOLOPYRONES HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1978-08-29 | — | — | US | claimed |
| US-4028383-A | DIMETHYLSULFONE REACTED WITH AN ESTER OF A SUBSTITUTED INDOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1977-06-07 | — | — | US | claimed |
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |
| US-4188326-A | Indolopyrones having anti-allergic activity | WARNER-LAMBERT COMPANY (US) | 1980-02-12 | — | — | US | disclosed |
| US-4175083-A | ANTIHISTAMINES, ANTIALLERGENS | WARNER-LAMBERT COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| US-4110464-A | INDOLOPYRONES HAVING ANTIALLERGIC ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4087443-A | ANTIALLERGENS, ASTHMA | WARNER-LAMBERT COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4028383-A | DIMETHYLSULFONE REACTED WITH AN ESTER OF A SUBSTITUTED INDOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1977-06-07 | — | — | US | disclosed |