Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278189 | 0.88 | KDM4E (0.50) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11267104 | 0.83 | CYP1A2 (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11277795 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11274440 | 0.81 | HSD17B10 (0.51) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL11284580 | 0.74 | CSNK2A2 (0.39) | KDM4EALDH1A1LMNACSNK2A2CSNK2B | |
| SCHEMBL11269382 | 0.74 | HPGD (0.39) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL11133282 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10654409 | 0.72 | PABPC1 (0.42) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL11274923 | 0.72 | GPR35 (0.43) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL7384714 | 0.71 | POLB (0.54) | EGFRKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |