SCHEMBL11274680

SCHEMBL11274680

CS(=O)(=O)c1ccc(C(O)Cn2ccnc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.63
HMOX1 P09601 1/20 0.59
CYP51A1 Q16850 1/20 0.55
TBXAS1 P24557 1/20 0.49
ADRA2C P18825 1/20 0.45
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696334 0.84 TBXAS1 (0.50) CYP19A1HMOX1TBXAS1ALDH1A1
SCHEMBL9661518 0.84 CYP19A1 (0.60) CYP19A1HMOX1CYP51A1
SCHEMBL9263044 0.83 TBXAS1 (0.52) CYP19A1TBXAS1ALDH1A1
SCHEMBL11983140 0.81 CYP19A1 (0.72) CYP19A1HMOX1CYP51A1ADRA2C
SCHEMBL4313095 0.81 CYP19A1 (0.72) CYP19A1HMOX1CYP51A1ADRA2C
SCHEMBL10932073 0.79 CYP19A1 (0.73) CYP19A1HMOX1CYP51A1ADRA2C
SCHEMBL11449998 0.78 TBXAS1 (0.51) CYP19A1HMOX1TBXAS1ALDH1A1
SCHEMBL6299999 0.78 CYP19A1 (0.72) CYP19A1HMOX1CYP51A1
SCHEMBL7562437 0.78 CYP19A1 (0.72) CYP19A1HMOX1CYP51A1
SCHEMBL11266884 0.78 CYP19A1 (0.72) CYP19A1HMOX1CYP51A1ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349556-A Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed