SCHEMBL11274684

SCHEMBL11274684

Nc1ccc(OCCc2ccc(F)cc2)nc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ELOVL1 Q9BW60 7/20 0.57
TAAR1 Q96RJ0 1/20 0.46
MAOB P27338 4/20 0.45
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KEAP1 Q14145 1/20 0.39
GFER P55789 1/20 0.38
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11181089 0.85 TAAR1 (0.44) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL11281491 0.85 CYP1A2 (0.44) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL30354806 0.85 TAAR1 (0.44) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL25381620 0.85 RAB9A (0.59) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL3365264 0.85 MEN1 (0.60) MEN1KMT2AKDM4EELOVL1MAOB
SCHEMBL25383372 0.84 TAAR1 (0.49) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL25381753 0.83 TAAR1 (0.50) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL17006857 0.80 ELOVL1 (0.57) MEN1KMT2AKDM4EELOVL1TAAR1
SCHEMBL23634035 0.80 KDM4E (0.50) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL29837272 0.80 KDM4E (0.50) MEN1KMT2AKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4334912-A HERBICIDES WHICH ARE NONPHYTOTOXIC TO CROPS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US disclosed