Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498465 | 0.88 | CYP1A2 (0.53) | MAPTLMNATSHRCYP1A2ACHE | |
| SCHEMBL3659342 | 0.84 | ACHE (0.66) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| SCHEMBL10774314 | 0.84 | ACHE (0.66) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL11268921 | 0.83 | AKR1C3 (0.58) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| SCHEMBL5051552 | 0.79 | UGT2B7 (0.66) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| SCHEMBL851238 | 0.79 | UGT2B7 (0.66) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| SCHEMBL5032107 | 0.79 | UGT2B7 (0.66) | ADRA1AADRA2ACYP2D6RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL11281582 | 0.79 | CYP1A2 (0.48) | ADRA1AADRA2ACYP2D6MAPTLMNA | |
| SCHEMBL25627482 | 0.78 | CYP1A2 (0.57) | CYP2D6MAPTLMNATSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL836425 | 0.77 | UGT2B7 (0.63) | ADRA1AADRA2ACYP2D6RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |