Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278647 | 0.80 | NPSR1 (0.42) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL19444921 | 0.75 | KDM4E (0.37) | NPSR1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL14020797 | 0.74 | KCNA5 (0.44) | NPSR1CA2CA4CA5ALMNA | |
| Triphenylphosphine Oxide SCHEMBL513223 | 0.74 | CA2 (0.58) | NPSR1CA2CA4CA5ALMNA | |
| Triphenylphosphine Oxide SCHEMBL3949 | 0.74 | CA2 (0.58) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL17589451 | 0.73 | NPSR1 (0.55) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL11283350 | 0.73 | CA2 (0.46) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL14076801 | 0.73 | CA2 (0.41) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL11280043 | 0.73 | MAPT (0.43) | NPSR1CA2CA4CA5ALMNA | |
| SCHEMBL10318987 | 0.72 | PLAU (0.44) | NPSR1LMNACFTRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330461-A | FIREPROOFING POLYESTERS AND POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4234729-A | FIREPROOFING POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-18 | — | — | US | disclosed |