SCHEMBL11280043

SCHEMBL11280043

O=P(c1ccccc1)(c1ccccc1)c1nc2ccccc2nc1P(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.43
▸ ALDH1A1 P00352 6/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ NPSR1 Q6W5P4 7/20 0.40
▸ KDM4E B2RXH2 6/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ GAA P10253 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ HPGD P15428 2/20 0.39
▸ ALOX12 P18054 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11275569 0.86 NPSR1 (0.44) MAPTALDH1A1SMN1; SMN2NPSR1KDM4E
SCHEMBL29156714 0.78 ALDH1A1 (0.41) MAPTALDH1A1NPSR1KMT2AHTT
SCHEMBL16401011 0.78 KDM4E (0.47) MAPTALDH1A1SMN1; SMN2KDM4EKMT2A
Lithium Ion SCHEMBL16401318 0.77 ALDH1A1 (0.39) MAPTALDH1A1SMN1; SMN2NPSR1KDM4E
SCHEMBL16401320 0.77 KDM4E (0.46) MAPTALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL11275777 0.75 USP8 (0.41) MAPTALDH1A1SMN1; SMN2CA2CA4
SCHEMBL14020797 0.74 KCNA5 (0.44) MAPTALDH1A1CA2CA4CA5A
SCHEMBL22837219 0.74 TLR8 (0.37) MAPTALDH1A1SMN1; SMN2NPSR1KDM4E
Triphenylphosphine Oxide SCHEMBL3949 0.74 CA2 (0.58) MAPTALDH1A1CA2CA4CA5A
Triphenylphosphine Oxide SCHEMBL513223 0.74 CA2 (0.58) MAPTALDH1A1CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080241589-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 — — US disclosed
US-20080241589-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 — — US disclosed
US-20080238307-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT FUJIFILM CORPORATION (JP) 2008-10-02 — — US disclosed
US-20080238307-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT FUJIFILM CORPORATION (JP) 2008-10-02 — — US disclosed
US-20080241518-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2008-10-02 — — US disclosed
US-20080241518-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2008-10-02 — — US disclosed
US-4330461-A FIREPROOFING POLYESTERS AND POLYAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-18 — — US disclosed
US-4234729-A FIREPROOFING POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241589-A1 ORGANIC ELECTROLUMINESCENT DEVICE OR10J3, AOC2, L1CAM MAPT 1515/4885ALDH1A1 196/4885SMN1; SMN2 4183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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