Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259353 | 0.94 | ACE (0.68) | ACELMNASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11292868 | 0.94 | ACE (0.69) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL3126925 | 0.88 | ACE (0.80) | ACELMNASMN1; SMN2 | |
| Enalaprilat Anhydrous SCHEMBL7258975 | 0.83 | ACE (0.88) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL24506200 | 0.82 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL11262743 | 0.82 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL11267471 | 0.82 | ACE (0.77) | ACELMNASMN1; SMN2 | |
| SCHEMBL11262921 | 0.82 | ACE (0.78) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11267866 | 0.82 | ACE (0.78) | ACELMNASMN1; SMN2CYP3A4 | |
| SCHEMBL7324222 | 0.82 | ACE (0.87) | ACELMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049506-A1 | N-carboxyalkyl dipeptides, a process for preparing and a pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | disclosed |