Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11438218 | 0.91 | — | — | |
| Bicarbonate SCHEMBL11274973 | 0.82 | — | — | |
| Nitrous Acid SCHEMBL17180228 | 0.80 | — | — | |
| Nitrous Acid SCHEMBL11586179 | 0.80 | ALDH1A1 (0.75) | ALDH1A1ALOX15TDP1CA1CA2 | |
| Nitrous Acid SCHEMBL311408 | 0.80 | — | — | |
| Bicarbonate SCHEMBL28225161 | 0.78 | — | — | |
| Bicarbonate SCHEMBL28325840 | 0.78 | — | — | |
| Nitrous Acid SCHEMBL25419792 | 0.75 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL1657920 | 0.75 | ALDH1A1 (0.67) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL2377993 | 0.75 | ALDH1A1 (0.88) | ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |