Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL1331277 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL8933907 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL11586179 | 0.94 | ALDH1A1 (0.75) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL11219505 | 0.94 | ALDH1A1 (1.00) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL341 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL9079679 | 0.94 | ALDH1A1 (1.00) | ALDH1A1ALOX15TDP1 | |
| Nitrous Acid SCHEMBL8638727 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL4730863 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL10973173 | 0.88 | — | — | |
| Nitrous Acid SCHEMBL2716956 | 0.88 | ALDH1A1 (0.88) | ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110236760-A1 | Electrode for non-aqueous electrolyte secondary battery, method for producing the same, and non-aqueous electrolyte secondary battery | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110229767-A1 | Electrode for non-aqueous electrolyte secondary battery, method for producing the same, and non-aqueous electrolyte secondary battery | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-09-22 | — | — | US | disclosed |
| US-20080119620-A1 | Curable Composition | TORAY FINE CHEMICALS CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1897913-A1 | CURABLE COMPOSITION | Toray Fine Chemicals Co., Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
| CN-101031618-A | Curable composition | TORAY FINECHEMICALS CO LTD (JP) | 2007-09-05 | — | — | CN | disclosed |