Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18100110 | 0.87 | XIAP (0.46) | XIAPALOX5MEN1KMT2APOLB | |
| SCHEMBL12637476 | 0.81 | HPGD (0.42) | POLBMAPTNPC1RAB9AHTT | |
| SCHEMBL29843187 | 0.77 | RAB9A (0.53) | XIAPMEN1KMT2APOLBMAPT | |
| SCHEMBL2170681 | 0.77 | RAB9A (0.53) | XIAPMEN1KMT2APOLBMAPT | |
| SCHEMBL4139521 | 0.75 | RAB9A (0.51) | XIAPMEN1KMT2APOLBMAPT | |
| SCHEMBL12591069 | 0.75 | HTT (0.41) | NPC1RAB9AHTTHPGDSMN1; SMN2 | |
| SCHEMBL1801464 | 0.74 | ALDH1A1 (0.52) | XIAPMEN1KMT2APOLBMAPT | |
| Iodomethane SCHEMBL9193628 | 0.74 | RAB9A (0.50) | XIAPMEN1KMT2APOLBMAPT | |
| SCHEMBL16705553 | 0.73 | TLR8 (0.46) | XIAPMEN1KMT2APOLBMAPT | |
| Bromide SCHEMBL4961408 | 0.73 | ALDH1A1 (0.50) | XIAPMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003141-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-ARYLENOTHIAZOLE COMPOUNDS AND THEIR RING N-SUBSTITUTED DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-14 | — | — | EP | disclosed |
| US-4252963-A | CYCLIZATION OF PHENYLTHIOUREAS WITH THIONYL CHLORIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| EP-0003141-A2 | Process for the preparation of 2-amino-arylenothiazole compounds and their ring N-substituted derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-25 | — | — | EP | disclosed |