Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252786 | 0.91 | OPRD1 (0.40) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11472896 | 0.86 | OPRD1 (0.38) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11472809 | 0.85 | OPRD1 (0.38) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11282490 | 0.84 | OPRD1 (0.42) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11286697 | 0.81 | C5AR1 (0.40) | OPRD1CYP2D6KCNH2 | |
| SCHEMBL11275302 | 0.80 | C5AR1 (0.40) | OPRD1CYP2D6KCNH2 | |
| SCHEMBL11258266 | 0.79 | OPRD1 (0.43) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11251548 | 0.79 | OPRD1 (0.39) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11254003 | 0.78 | OPRD1 (0.43) | OPRD1CYP2D6KCNH2KMT2ATRPV1 | |
| SCHEMBL11254515 | 0.77 | OPRD1 (0.38) | OPRD1CYP2D6KCNH2KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4195183-A | ω-Nor-aromatic-13,14-dehydro-prostaglandins and process for their preparation | Farmitalia Certo Erba S.p.A. (IT) | 1980-03-25 | — | — | US | disclosed |