Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511213 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL10862496 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL11271280 | 0.81 | MAPT (0.47) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL10881346 | 0.80 | KMT2A (0.39) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8797397 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL10864330 | 0.78 | DRD1 (0.52) | DRD2DRD3HTR2AHTR2BSIGMAR1 | |
| SCHEMBL11272147 | 0.78 | MAOB (0.43) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8614670 | 0.78 | TBXA2R (0.47) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL11152236 | 0.78 | DRD1 (0.56) | ALDH1A1MAPTGAAHPGDTDP1 | |
| SCHEMBL5400526 | 0.77 | HTR2A (0.44) | NPC1RAB9ASMN1; SMN2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335122-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-06-15 | — | — | US | disclosed |