Toluene

Toluene

SCHEMBL1127533

Cc1ccccc1.O=C(O)CC(=O)O

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58
ACHE P22303 1/20 0.58
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
SMN1; SMN2 Q16637 6/20 0.50
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
POLB P06746 1/20 0.50
LDHA P00338 1/20 0.47
SRR Q9GZT4 1/20 0.47
MAPT P10636 2/20 0.47
RECQL P46063 1/20 0.45
HPGD P15428 2/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL1452591 1.00 LMNA (0.58) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL28244172 1.00 LMNA (0.58) LMNATSHRALOX12ACHENPC1
Acetoacetic Acid SCHEMBL9704495 0.88 NPC1 (0.50) LMNATSHRALOX12ACHENPC1
Acetoacetic Acid SCHEMBL28140837 0.88 NPC1 (0.50) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL28869912 0.84 KMT2A (0.74) LMNANPC1RAB9AKMT2AMEN1
Succinic Acid SCHEMBL23045112 0.84 KMT2A (0.61) LMNATSHRALOX12ACHENPC1
Succinic Acid SCHEMBL6574726 0.84 KMT2A (0.61) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL1650313 0.84 LMNA (0.58) LMNATSHRALOX12ACHENPC1
Toluene SCHEMBL27592105 0.84 LMNA (0.58) LMNATSHRALOX12ACHENPC1
Malonic Acid Diethyl Ester SCHEMBL28691891 0.84 GAA (0.56) TSHRNPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060349-A Supermolecule aggregate surfactant 北京理工大学 2024-12-03 CN disclosed
CN-119060350-A Preparation method and application of supermolecule aggregate surfactant 北京理工大学 2024-12-03 CN disclosed
CN-207913739-U A kind of micro-fluidic reaction unit for the synthesis of radonil derivative 贵州理工学院 2018-09-28 CN disclosed
EP-2283002-A2 NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION Intermune, Inc. (US) 2011-02-16 EP disclosed
WO-2009134616-A2 NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION INTERMUNE, INC. (US) 2009-11-05 WO disclosed