Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010114 | 0.83 | MAPT (0.49) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL7650155 | 0.82 | MAPT (0.61) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL5009578 | 0.80 | MAPT (0.59) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL12342190 | 0.80 | MAPT (0.55) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL81551 | 0.80 | S100B (0.58) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL2759054 | 0.79 | MAPT (1.00) | MAPTHTTGAAPKMMCL1 | |
| Hydrochloric Acid SCHEMBL237984 | 0.79 | S100B (0.56) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL2759023 | 0.78 | MAPT (0.90) | MAPTHTTGAAPKMMCL1 | |
| Hydrochloric Acid SCHEMBL6373886 | 0.77 | S100B (0.55) | MAPTHTTGAAPKMMCL1 | |
| SCHEMBL16136833 | 0.77 | MAPT (0.85) | MAPTHTTGAAPKMMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |