SCHEMBL7650155

SCHEMBL7650155

CCN(CCO)c1ccc(C(c2ccccc2)c2ccc(N(CC)CCO)cc2C)c(C)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.61
GAA P10253 1/20 0.61
PKM P14618 1/20 0.61
HTT P42858 1/20 0.61
MCL1 Q07820 1/20 0.61
KMT2A Q03164 4/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
ATM Q13315 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MEN1 O00255 2/20 0.46
S1PR1 P21453 3/20 0.39
S100B P04271 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
PSMD14 O00487 1/20 0.38
MITF O75030 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12342190 0.90 MAPT (0.55) MAPTGAAPKMHTTMCL1
SCHEMBL13576324 0.90 MAPT (0.51) MAPTGAAPKMHTTMCL1
SCHEMBL133593 0.89 S100B (0.49) MAPTGAAPKMHTTMCL1
SCHEMBL7952524 0.89 S100B (0.49) MAPTGAAPKMHTTMCL1
SCHEMBL12342187 0.87 MAPT (0.58) MAPTGAAPKMHTTMCL1
Perchlorate SCHEMBL11345976 0.86 MAPT (0.48) MAPTGAAPKMHTTMCL1
SCHEMBL5009578 0.85 MAPT (0.59) MAPTGAAPKMHTTMCL1
SCHEMBL12342189 0.85 MAPT (0.50) MAPTGAAPKMHTTMCL1
SCHEMBL12342186 0.84 MAPT (0.43) MAPTGAAPKMHTTMCL1
SCHEMBL12342183 0.83 MAPT (0.44) MAPTGAAPKMHTTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361913-B1 ELECTROGRAPHY IMAGES, SUBSTRATES WITH CHARGE GENERATING LAYER AND CHARGE TRANSPORT LAYER, OVERCOATING AND HYDROXY TRIPHENYL METHANE XEROX CORPORATION 2002-03-26 US claimed
US-4258112-A AROMATIC AMINES, ISOBENZOFURANS OR JULOLIDINE, PHOTOSENSITIVE PIGMENT EASTMAN KODAK COMPANY (US) 1981-03-24 US claimed
EP-0010450-A1 Sensitized electrophoretic migration imaging dispersion and process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-30 EP claimed
EP-2130816-B1 Triarylmethanes and processes for making the same XEROX CORP (US) 2017-08-23 EP disclosed
US-8795934-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-05 US disclosed
US-8795934-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-05 US disclosed
US-20130252154-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-09-26 US disclosed
US-20130252154-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-09-26 US disclosed
US-8518617-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-08-27 US disclosed
US-8518617-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-08-27 US disclosed
US-8080351-B2 Triarylmethanes and processes for making the same XEROX CORPORATION (US) 2011-12-20 US disclosed
US-20100092883-A1 IMAGING MEMBER EXHIBITING LATERAL CHARGE MIGRATION RESISTANCE XEROX CORPORATION (US) 2010-04-15 US disclosed
EP-2130816-A1 Triarylmethanes and processes for making the same Xerox Corporation (US) 2009-12-09 EP disclosed
US-20090297960-A1 Triarylmethanes and Processes for Making the Same XEROX CORPORATION (US) 2009-12-03 US disclosed
US-20090297960-A1 Triarylmethanes and Processes for Making the Same XEROX CORPORATION (US) 2009-12-03 US disclosed
US-6361913-B1 ELECTROGRAPHY IMAGES, SUBSTRATES WITH CHARGE GENERATING LAYER AND CHARGE TRANSPORT LAYER, OVERCOATING AND HYDROXY TRIPHENYL METHANE XEROX CORPORATION 2002-03-26 US disclosed
US-5080989-A Polycarbonate, solvent resistance EASTMAN KODAK COMPANY (US) 1992-01-14 US disclosed
US-4361636-A COLORANT EASTMAN KODAK COMPANY (US) 1982-11-30 US disclosed
EP-0064007-A1 Ionic polyesters, electrically photosensitive composite particles and materials containing the polyesters and photoelectrophoretic imaging methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-11-03 EP disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297960-A1 Triarylmethanes and Processes for Making the Same ACAT1, GNPAT, AKR7A2 MAPT 526/4885GAA 612/4885PKM 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.