Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.49 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273998 | 0.95 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL11284143 | 0.94 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL11276748 | 0.94 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL11287493 | 0.94 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL11274355 | 0.92 | CYP19A1 (0.57) | CYP19A1CYP11B1CYP11B2CYP1A2POLB | |
| SCHEMBL11285718 | 0.90 | CYP11B1 (0.53) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL11270065 | 0.88 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL11286312 | 0.88 | ALDH1A1 (0.51) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL11272572 | 0.88 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL11276740 | 0.87 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |