Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184487 | 0.87 | HDAC3 (0.46) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL850672 | 0.83 | GAA (0.42) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL28675119 | 0.81 | GAA (0.46) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL1413000 | 0.80 | GAA (0.48) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL845247 | 0.79 | ALDH1A1 (0.47) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL9865139 | 0.78 | GAA (0.46) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL7713280 | 0.77 | GAA (0.55) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL11527633 | 0.76 | HSP90AA1 (0.53) | GAAALDH1A1KMT2A | |
| SCHEMBL6644483 | 0.75 | GAA (0.49) | GAASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL2539602 | 0.74 | GAA (0.42) | GAAMGAMSIMGAM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048044-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |