SCHEMBL845247

SCHEMBL845247

CCCCC(=O)NC(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MAPT P10636 4/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PKM P14618 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 3/20 0.44
HSP90AA1 P07900 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
FAAH O00519 1/20 0.41
HPGD P15428 1/20 0.41
ACHE P22303 1/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527633 0.92 HSP90AA1 (0.53) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL184487 0.87 HDAC3 (0.46) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL6644483 0.82 GAA (0.49) KMT2AKDM4EMEN1SMN1; SMN2GAA
SCHEMBL27963912 0.81 MAPT (0.46) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL28675119 0.81 GAA (0.46) ALDH1A1KMT2AKDM4ESMN1; SMN2GAA
SCHEMBL7440483 0.80 EPHX1 (0.53) ALDH1A1MAPTKMT2AMEN1HSP90AA1
SCHEMBL1413000 0.80 GAA (0.48) ALDH1A1KMT2AKDM4ESMN1; SMN2GAA
SCHEMBL5147801 0.79 ALDH1A1 (0.59) ALDH1A1MAPTKMT2AKDM4EMEN1
SCHEMBL11275622 0.79 GAA (0.39) ALDH1A1KMT2AKDM4ESMN1; SMN2GAA
SCHEMBL27818513 0.78 GAA (0.41) ALDH1A1MAPTKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689356-B Carbamate resins for polyurethane adhesives 普利司通美国轮胎运营有限责任公司 2021-07-02 CN disclosed
US-8759471-B2 Adhesion-promoting system for rubber goods ALLNEX GERMANY GMBH (DE) 2014-06-24 US disclosed
EP-2432810-B1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS ALLNEX GERMANY GMBH (DE) 2014-01-29 EP disclosed
CN-102459379-A Adhesion promoting system for rubber articles CYTEC SURFACE SPECIALTIES GERMANY GMBH 2012-05-16 CN disclosed
US-20120095152-A1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS CYTEC SURFACE SPECIALTIES GERMANY GMBH (DE) 2012-04-19 US disclosed
EP-2432810-A1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS Cytec Surface Specialties Germany GmbH (DE) 2012-03-28 EP disclosed
WO-2010133622-A1 ADHESION-PROMOTING SYSTEM FOR RUBBER GOODS CYTEC SURFACE SPECIALTIES GERMANY GMBH (DE) 2010-11-25 WO disclosed
EP-2253649-A1 Adhesion-promoting system for rubber goods Cytec Surface Specialties Germany GmbH & Co. KG (DE) 2010-11-24 EP disclosed
EP-0412594-B1 Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists MERCK & CO INC (US) 1996-01-03 EP disclosed
US-5411980-A Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists MERCK & CO., INC. (US) 1995-05-02 US disclosed
EP-0586513-A1 ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS MERCK & CO. INC. (US) 1994-03-16 EP disclosed
US-5281614-A Hypotensive agents, glaucoma or angiotensin antagonists MERCK & CO., INC. (US) 1994-01-25 US disclosed
WO-1993001177-A1 SUBSTITUTED TRIAZOLINONES MERCK & CO., INC. (US) 1993-01-21 WO disclosed
WO-1992020662-A1 ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS MERCK & CO., INC. (US) 1992-11-26 WO disclosed
EP-0412594-A2 Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists MERCK & CO. INC. (US) 1991-02-13 EP disclosed