Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265517 | 0.78 | APEX1 (0.45) | APEX1CA12CA9GLAKDM4E | |
| SCHEMBL11272059 | 0.78 | APEX1 (0.47) | APEX1CA12CA9GLAKDM4E | |
| SCHEMBL11282506 | 0.76 | ALDH1A1 (0.51) | CA12CA9KDM4EMEN1KMT2A | |
| SCHEMBL11275890 | 0.75 | ALDH1A1 (0.51) | APEX1CA12CA9GLAKDM4E | |
| SCHEMBL11270472 | 0.75 | CA12 (0.45) | APEX1CA12CA9ALOX15GLA | |
| SCHEMBL11280487 | 0.67 | KDM4E (0.42) | APEX1CA12CA9GLAKDM4E | |
| SCHEMBL18180193 | 0.66 | APEX1 (0.77) | APEX1GLAKDM4EMEN1KMT2A | |
| SCHEMBL11271085 | 0.66 | ALDH1A1 (0.52) | CA12CA9KDM4EMEN1KMT2A | |
| SCHEMBL11277993 | 0.66 | ALDH1A1 (0.52) | CA12CA9KDM4EMEN1KMT2A | |
| SCHEMBL4559216 | 0.66 | ALDH1A1 (0.62) | APEX1GLAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337265-A | COMPLICATIONS OF DIABETES | AYERST, MCKENNA & HARRISON INC. (CA) | 1982-06-29 | — | — | US | claimed |