Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272059 | 0.82 | APEX1 (0.47) | KDM4EAPEX1CA12CA9GLA | |
| SCHEMBL11265517 | 0.73 | APEX1 (0.45) | KDM4EAPEX1CA12CA9GLA | |
| SCHEMBL11270472 | 0.73 | CA12 (0.45) | KDM4EAPEX1CA12CA9GLA | |
| SCHEMBL11279531 | 0.72 | ALDH1A1 (0.48) | KDM4ECA12CA9L3MBTL1ALDH1A1 | |
| SCHEMBL11282506 | 0.68 | ALDH1A1 (0.51) | KDM4ECA12CA9L3MBTL1ALDH1A1 | |
| SCHEMBL11275890 | 0.67 | ALDH1A1 (0.51) | KDM4EAPEX1CA12CA9GLA | |
| SCHEMBL11275635 | 0.67 | APEX1 (0.45) | KDM4EAPEX1CA12CA9GLA | |
| SCHEMBL11279146 | 0.66 | APEX1 (0.49) | KDM4EAPEX1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4494789 | 0.64 | KDM4E (0.69) | KDM4EAPEX1GLAL3MBTL1ALDH1A1 | |
| SCHEMBL11192533 | 0.62 | MAPT (0.53) | KDM4EAPEX1GLAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337265-A | COMPLICATIONS OF DIABETES | AYERST, MCKENNA & HARRISON INC. (CA) | 1982-06-29 | — | — | US | claimed |