Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | RGS12 | O14924 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | THPO | P40225 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756841 | 0.89 | PTGS1 (0.71) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL21617912 | 0.87 | PTGS1 (0.63) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL31443016 | 0.84 | CA2 (0.63) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL8813563 | 0.84 | CA2 (0.63) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL6513131 | 0.84 | AKR1B1 (0.65) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL8742249 | 0.82 | PTGS1 (0.64) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL11461095 | 0.82 | CA2 (0.59) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL21585562 | 0.82 | CA2 (0.61) | GAATSHRKDM4EMAPTHPGD | |
| Methane SCHEMBL9087531 | 0.82 | CA2 (0.61) | GAATSHRKDM4EMAPTHPGD | |
| SCHEMBL21585550 | 0.82 | PTGS1 (0.62) | GAATSHRKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |