SCHEMBL11276165

SCHEMBL11276165

Oc1cccc(OCc2ccc(Cl)cc2Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.68
NR4A1 P22736 1/20 0.68
NR4A3 Q92570 1/20 0.68
HPD P32754 1/20 0.55
ALDH1A1 P00352 2/20 0.52
MAPT P10636 1/20 0.52
NCOA1 Q15788 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NCOA3 Q9Y6Q9 1/20 0.52
IDO1 P14902 2/20 0.50
IGF1R P08069 1/20 0.50
FABP3 P05413 1/20 0.50
FABP4 P15090 1/20 0.50
FABP5 Q01469 1/20 0.50
KMT2A Q03164 2/20 0.49
INPPL1 O15357 2/20 0.49
MEN1 O00255 1/20 0.49
NPSR1 Q6W5P4 2/20 0.48
UBE2N P61088 1/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22964337 0.84 NR4A2 (0.50) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL11704301 0.83 NR4A2 (0.63) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL2562469 0.82 NR4A2 (0.61) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL11705156 0.81 NR4A2 (0.60) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL5838953 0.81 NR4A2 (1.00) NR4A2NR4A1NR4A3HPDFABP3
SCHEMBL12516120 0.79 NR4A2 (0.61) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL31533129 0.78 APP (0.70) NR4A2HPDSMN1; SMN2KMT2AMEN1
SCHEMBL4697290 0.78 APP (0.70) NR4A2HPDSMN1; SMN2KMT2AMEN1
SCHEMBL11085911 0.77 NR4A2 (0.55) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL4698486 0.77 NR4A2 (0.66) NR4A2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044536-A1 Plant growth regulators and their use J.T. Baker Chemical Co. (US) 1982-01-27 EP disclosed