SCHEMBL31533129

SCHEMBL31533129

Oc1cccc(OCc2ccc(Cl)cc2)c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.70
NR4A2 P43354 1/20 0.65
MAOB P27338 7/20 0.63
MAOA P21397 3/20 0.63
RXRA P19793 1/20 0.56
RXRB P28702 1/20 0.56
RXRG P48443 1/20 0.56
SMPD1 P17405 1/20 0.56
MEN1 O00255 1/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TLR4 O00206 1/20 0.52
TLR2 O60603 1/20 0.52
HPD P32754 1/20 0.52
SPHK2 Q9NRA0 1/20 0.51
SPHK1 Q9NYA1 1/20 0.51
F2 P00734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4697290 1.00 APP (0.70) APPNR4A2MAOBMAOARXRA
SCHEMBL27735405 0.87 APP (0.77) APPMAOBMEN1KMT2AF2
SCHEMBL4699232 0.85 GPR84 (0.52) APPNR4A2MAOBMAOA
SCHEMBL4698486 0.84 NR4A2 (0.66) APPNR4A2MAOBMAOARXRA
SCHEMBL29548398 0.83 APP (0.71) APPNR4A2MAOBMAOASMPD1
SCHEMBL384725 0.83 APP (0.71) APPNR4A2MAOBMAOASMPD1
SCHEMBL11121827 0.83 SMN1; SMN2 (0.66) NR4A2MAOBMAOARXRARXRB
SCHEMBL22964317 0.82 MAOB (0.58) APPNR4A2MAOBMAOARXRA
SCHEMBL18429651 0.82 APP (1.00) APPMAOBRXRARXRBF2
SCHEMBL11300058 0.82 MAOB (0.70) APPNR4A2MAOBMAOAHPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569635-A Biaryl ring inhibitors targeting c-Myc proteins 上海深势唯思科技有限责任公司 2025-03-07 CN disclosed