SCHEMBL2562469

SCHEMBL2562469

OB(O)c1cccc(OCc2ccc(Cl)cc2Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 3/20 0.61
NR4A1 P22736 1/20 0.61
NR4A3 Q92570 1/20 0.61
HPD P32754 1/20 0.51
ALDH1A1 P00352 2/20 0.48
MAPT P10636 1/20 0.48
NCOA1 Q15788 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
IGF1R P08069 1/20 0.46
FABP3 P05413 1/20 0.46
FABP4 P15090 1/20 0.46
FABP5 Q01469 1/20 0.46
KMT2A Q03164 3/20 0.45
INPPL1 O15357 2/20 0.45
MEN1 O00255 2/20 0.45
IDO1 P14902 2/20 0.45
ENPP2 Q13822 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
UBE2N P61088 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2558815 0.86 NR4A2 (0.46) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL21763 0.85 NR4A2 (0.59) NR4A2NR4A1NR4A3MAPTKMT2A
SCHEMBL29663864 0.85 NR4A2 (0.59) NR4A2NR4A1NR4A3MAPTKMT2A
SCHEMBL2562346 0.84 NR4A2 (0.62) NR4A2NR4A1NR4A3ALDH1A1MAPT
SCHEMBL11276165 0.82 NR4A2 (0.68) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL23988 0.81 NR4A2 (0.58) NR4A2HPDSMN1; SMN2KMT2AMEN1
SCHEMBL21408 0.79 NR4A2 (0.59) NR4A2ENPP2NPC1RAB9ACYP1A2
SCHEMBL2562164 0.79 ENPP2 (0.50) NR4A2ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL11704301 0.78 NR4A2 (0.63) NR4A2NR4A1NR4A3HPDALDH1A1
SCHEMBL2560441 0.78 HPD (0.47) NR4A2NR4A1NR4A3HPDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed