SCHEMBL11276174

SCHEMBL11276174

Cc1ccc(I)c(C)c1Br

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
PKM P14618 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3735662 0.79 NCEH1 (0.41) ALDH1A1MEN1CYP1A2PKMTSHR
SCHEMBL10753626 0.77 NCEH1 (0.42) ALDH1A1MEN1CYP1A2PKMTSHR
SCHEMBL8257514 0.75 KDM4E (0.39) ALDH1A1
SCHEMBL22864465 0.75
SCHEMBL27439116 0.75 NOTUM (0.34)
SCHEMBL8527219 0.75 CYP1A2 (0.35) CYP1A2TSHR
SCHEMBL31668870 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2TSHR
SCHEMBL21218770 0.73 ACHE (0.33) TSHR
SCHEMBL819186 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2TSHR
SCHEMBL21624583 0.72 POLB (0.31) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134520-B Thermal activation delay material and organic photoelectric device comprising same 上海天马有机发光显示技术有限公司 2021-08-03 CN disclosed
CN-105392863-A Composition and light-emitting element using the same SUMITOMO CHEMICAL CO 2016-03-09 CN disclosed
EP-0058047-A1 Substituted imidazole derivatives and their preparation and use Farmos-Yhtyma Oy (FI) 1982-08-18 EP disclosed