Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423797 | 0.88 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL29213956 | 0.85 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10900761 | 0.85 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL30235602 | 0.85 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6865758 | 0.83 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL28882273 | 0.82 | CES2 (0.62) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11271901 | 0.81 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6970291 | 0.80 | CES2 (0.61) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28423545 | 0.79 | FFAR4 (0.53) | MEN1KMT2AMAPTLMNANR4A2 | |
| SCHEMBL11268575 | 0.79 | MEN1 (0.56) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319916-A | 3-Acyl-5-phenyl-4(1H)-pyridinones and their use as herbicides | ELI LILLY AND COMPANY (US) | 1982-03-16 | — | — | US | disclosed |